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In Vivo. 2007 Mar-Apr;21(2):365-70.

Review. Pro- and anti-angiogenesis effects of resveratrol.

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Department of Surgery, Far Eastern Memorial Hospital, 21, Sec. 2, Nan-Ya South Road, Banciao, Taipei 220, Taiwan.

Erratum in

  • In Vivo. 2007 Sep-Oct;21(5):955.
  • In Vivo. 2007 Nov-Dec;21(6):1172.


Resveratrol, a natural polyphenol, has a variety of effects including protection against ischemia-reperfusion injury, and antitumor and chemopreventive action against malignant tumors. In recent years, resveratrol has been found to exert pro-and anti-angiogenic effects, depending on the situation. For example, pro-angiogenic effects are noted in the peri-infarct myocardium, whereas resveratrol inhibits angiogenesis in tumors. In this article, a review of the literature concerning both pro-angiogenic and anti-angiogenic effects of resveratrol and the underlying mechanisms of its effects on angiogenesis is presented.

[Indexed for MEDLINE]
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