Format

Send to

Choose Destination
See comment in PubMed Commons below
Curr Opin Drug Discov Devel. 2007 Mar;10(2):185-92.

Discovery and development of therapeutic cancer vaccines.

Author information

1
Transgene SA, Department of Medical Affairs, 11 rue de Molsheim, 67082 Strasbourg, France. acres@transgene.fr

Abstract

Over the past century, various efforts have been made to induce the rejection of cancerous tissues by the stimulation of an immune reaction, using both non-specific and antigen-specific strategies. Non-specific approaches attempt to augment an immune response in and around the tumor by injecting immune stimulating substances, for example, bacterial extracts, cytokines or gene therapy agents. Antigen-specific approaches use either the tumor cells themselves as a source of antigens or incorporate identified tumor-associated antigens into vaccines. This review describes antigen-specific therapeutic cancer vaccines that are currently in development.

PMID:
17436554
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center