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Fertil Steril. 2007 Sep;88(3):629-31. Epub 2007 Apr 16.

Ectopic pregnancy rates with frozen compared with fresh blastocyst transfer.

Author information

1
Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California 94304, USA.

Abstract

OBJECTIVE:

To compare the rate of ectopic pregnancy (EP) with fresh versus frozen blastocyst transfer in our program during the same time period.

DESIGN:

Retrospective analysis.

SETTING:

University IVF program.

PATIENT(S):

Women who achieved a clinical pregnancy after IVF between 1998 and 2005.

INTERVENTION(S):

In our program, cryopreservation is performed at the blastocyst stage. Embryo transfer was performed 1 to 1.5 cm short of the fundus by abdominal ultrasound guidance.

MAIN OUTCOME MEASURE(S):

The incidence of EP was examined in relation to fresh versus frozen blastocyst transfer.

RESULT(S):

In the frozen blastocyst group, there were 5 EPs out of 180 clinical pregnancies (2.8%), and there were 10 EPs out of 564 clinical pregnancies (1.8%) in the fresh blastocyst group.

CONCLUSION(S):

The rate of EP is not significantly increased after the transfer of frozen thawed blastocysts compared with fresh blastocyst transfer.

[Indexed for MEDLINE]

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