Format

Send to

Choose Destination
See comment in PubMed Commons below
Cell. 2007 Apr 6;129(1):33-6.

Development in motion: helper T cells at work.

Author information

1
Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. sreiner@mail.med.upenn.edu <sreiner@mail.med.upenn.edu>

Abstract

In mammals, helper T cells orchestrate defense against diverse pathogens. However, these warriors of the immune system can also result in self-inflicted injury culminating in autoimmune and allergic diseases. Recent findings--such as the discovery of the Th17 lineage--have revealed additional complexity in the fates chosen by helper T cells and have begun to reshape our view of how signaling and transcriptional networks generate appropriate and inappropriate immunity.

PMID:
17418783
DOI:
10.1016/j.cell.2007.03.019
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center