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Clin Infect Dis. 2007 May 1;44(9):1216-9. Epub 2007 Mar 19.

Evaluation of polymerase chain reaction and culture for diagnosis of pertussis in the control of a county-wide outbreak focused among adolescents and adults.

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1
Wisconsin Division of Public Health, Madison, WI 53702, USA. sotirmj@dhfs.state.wi.us

Abstract

During a large pertussis outbreak, culture and polymerase chain reaction (PCR) were used to identify 149 case patients; of these case patients, 79 had positive PCR and culture results, 59 had positive PCR results and negative culture results, 11 had negative PCR results and positive culture results (10 PCR-negative, culture-positive specimens were collected < or = 14 days after illness onset). PCR and culture of samples obtained < or = 2 weeks after illness onset and PCR of samples obtained > 2 weeks after illness onset proved to be most diagnostically useful.

PMID:
17407041
DOI:
10.1086/513432
[Indexed for MEDLINE]
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