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J Dermatol Surg Oncol. 1992 Jan;18(1):17-21.

Treatment of glabellar frown lines with C. botulinum-A exotoxin.

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Department of Opthalmology, University of British Columbia, Vancouver, Canada.


Eighteen patients with glabellar frown lines were treated with C. botulinum-A exotoxin. Sixteen of the 17 patients followed showed improvement for periods ranging from 3 months to 11 months. Side-effects were minimal and transient. Because C. botulinum-A exotoxin therapy of glabellar frown lines treats the underlying cause of these lines, it is more effective than soft tissue augmentation although this improvement is temporary. Treatment with C. botulinum-A exotoxin is a simple, safe procedure.

[Indexed for MEDLINE]

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