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Int J Tuberc Lung Dis. 2007 Apr;11(4):412-6.

Outcomes of tuberculosis patients who start antiretroviral therapy under routine programme conditions in Malawi.

Author information

1
Clinical HIV Unit, Ministry of Health, Lilongwe 3, Malawi.

Abstract

SETTING:

Public sector facilities in Malawi providing antiretroviral therapy (ART) to human immunodeficiency virus (HIV) positive patients, including those with tuberculosis (TB).

OBJECTIVES:

To compare 6-month and 12-month cohort treatment outcomes of HIV-positive TB patients and HIV-positive non-TB patients treated with ART.

DESIGN:

Retrospective data collection using ART patient master cards and ART patient registers.

RESULTS:

Between July and September 2005, 7905 patients started ART, 6967 with a non-TB diagnosis and 938 with a diagnosis of active TB. 6-month cohort outcomes of non-TB and TB patients censored on 31 March 2006 showed significantly more TB patients alive and on ART (77%) compared with non-TB patients (71%) (P < 0.001). Between January and March 2005, 4580 patients started ART, 4179 with a non-TB diagnosis and 401 with a diagnosis of active TB. 12-month cohort outcomes of non-TB and TB patients censored on 31 March 2006 showed significantly more TB patients alive and on ART (74%) compared with non-TB patients (66%) (P < 0.001). Other outcomes of default and transfer out were also significantly less frequent in TB compared with non-TB patients.

CONCLUSION:

HIV-positive TB patients on ART in Malawi have generally good treatment outcomes, and more patients need to access this HIV treatment.

PMID:
17394687
[Indexed for MEDLINE]

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