Abstract
A new xanthone named cratoxylumxanthone A (1), together with five known compounds: dulcisxanthone B (2), alpha-mangostin (3), beta-mangostin (4), 2-geranyl-1,3,7-trihydroxy-4-(3-methylbut-2-enyl)xanthone (5) and tectochrystin (6), was isolated from Cratoxylum cochinchinense stems. The structure of new compound was characterized by 1D and 2D NMR techniques. The isolated compounds showed free radical scavenging against DPPH and lipid peroxidation inhibition.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antioxidants / chemistry*
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Antioxidants / isolation & purification
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Antioxidants / pharmacology*
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Biphenyl Compounds / metabolism
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Clusiaceae / chemistry*
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification
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Free Radical Scavengers / pharmacology
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Hydrazines / metabolism
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Lipid Peroxides / metabolism
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Nuclear Magnetic Resonance, Biomolecular
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Picrates
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Plant Stems / chemistry
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Rats
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Spectrometry, Mass, Electrospray Ionization
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Spectrophotometry, Ultraviolet
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Thiobarbituric Acid Reactive Substances / metabolism
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Xanthones / chemistry*
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Xanthones / isolation & purification
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Xanthones / pharmacology*
Substances
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Antioxidants
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Biphenyl Compounds
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Free Radical Scavengers
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Hydrazines
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Lipid Peroxides
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Picrates
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Plant Extracts
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Thiobarbituric Acid Reactive Substances
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Xanthones
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1,1-diphenyl-2-picrylhydrazyl