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Biometals. 2007 Oct;20(5):793-6. Epub 2007 Mar 28.

Iron-citrate complexes and free radicals generation: is citric acid an innocent additive in foods and drinks?

Author information

1
Laboratoire de Chimie Biomimétique, LEDSS, UMR CNRS 5616, Université Joseph Fourier, BP 53, 38041, Grenoble Cedex 9, France. Isabelle.Gautier-Luneau@grenoble.cnrs.fr

Abstract

The generation of free radicals (Fenton chemistry) from various iron citrate complexes has been studied. Spin trapping methods have been used. The results can question concerning the innocence of added citric acid in foods and cold drinks. We concluded that in absence of pathological situation citric acid is probably not dangerous but it may become dangerous in situation of oxidative stress and/or iron overload.

PMID:
17390216
DOI:
10.1007/s10534-006-9042-y
[Indexed for MEDLINE]

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