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Dig Dis Sci. 2007 May;52(5):1199-205.

Progress of study on the relationship between mediators of inflammation and apoptosis in acute pancreatitis.

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1
Department of General Surgery, Hangzhou First People's Hospital, Hangzhou, 310006, Zhejiang Province, China. zxp99688@vip.163.com

Abstract

As an important pathological feature of acute pancreatitis, apoptosis may occur in multiple organs and relate directly to the progression of disease. It is mainly controlled by the apoptosis gene and also influenced by inflammatory mediators. We summarize here the roles of the main inflammatory mediators (e.g., NO, TNF-alpha, TGF-beta1, IL-10, NF-kappaB) during the pathologic process of acute pancreatitis.

PMID:
17372825
DOI:
10.1007/s10620-006-9388-6
[Indexed for MEDLINE]
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