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Emerg Infect Dis. 2007 Jan;13(1):18-24.

Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh.

Author information

1
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh. icddrb@gmail.com

Abstract

Approximately 20,000 stool specimens from patients with diarrhea visiting 1 urban and 1 rural hospital in Bangladesh during January 2001-May 2006 were tested for group A rotavirus antigen, and 4,712 (24.0%) were positive. G and P genotyping was performed on a subset of 10% of the positive samples (n = 471). During the 2001-2005 rotavirus seasons, G1P[8] (36.4%) and G9P[8] (27.7%) were the dominant strains, but G2[4] and G12P[6] were present in 15.4% and 3.1% of the rotavirus-positive patients, respectively. During the 2005-06 rotavirus season, G2P[4] (43.2%) appeared as the most prevalent strain, and G12P[6] became a more prevalent strain (11.1%) during this season. Because recently licensed rotavirus vaccines include only the P[8] specificity, it is unknown how the vaccines will perform in settings where non-P[8] types are prevalent.

PMID:
17370511
PMCID:
PMC2725799
DOI:
10.3201/eid1301.060910
[Indexed for MEDLINE]
Free PMC Article

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