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Curr Opin Microbiol. 2007 Apr;10(2):152-5. Epub 2007 Mar 21.

Small RNAs controlling outer membrane porins.

Author information

1
Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense M, Denmark. valentin@bmb.sdu.dk

Abstract

Gene regulation by small non-coding RNAs has been recognized as an important post-transcriptional regulatory mechanism for several years. In Gram-negative bacteria such as Escherichia coli and Salmonella, these RNAs control stress response and translation of outer membrane proteins and therefore are key regulators of environmental stress. Recent work has revealed an intimate interplay between small RNA regulation of outer membrane proteins and the stress-induced sigmaE-signalling system, which has an essential role in the maintenance of the integrity of the outer membrane.

PMID:
17369078
DOI:
10.1016/j.mib.2007.03.001
[Indexed for MEDLINE]

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