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Blood Rev. 2007 Sep;21(5):255-65. Epub 2007 Mar 26.

Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma.

Author information

1
Division of Hematology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, United States. rajkumar.vincent@mayo.edu

Abstract

Monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) are asymptomatic disorders characterized by monoclonal plasma cell proliferation in the bone marrow in the absence of end-organ damage. Updated diagnostic criteria for these disorders, risk-stratification models to determine prognosis, and the current management of these two entities are discussed in this review.

PMID:
17367905
DOI:
10.1016/j.blre.2007.01.002
[Indexed for MEDLINE]

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