Olmsted syndrome in an Iranian family: report of two new cases

Arch Iran Med. 2007 Apr;10(2):246-9.

Abstract

Olmsted syndrome is a rare congenital entity characterized by combination of symmetrical, sharply-defined palmoplantar keratoderma with flexion deformities of the digits, periorificial keratosis, perianal involvement, onychodystrophy, and variable leukokeratosis. Herein, we report two new related male patients--the third familial cases of Olmsted syndrome--one with the full-blown spectrum of the syndrome, and the other with early signs and symptoms of the disorder.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Child
  • Disease Progression
  • Humans
  • Iran
  • Keratoderma, Palmoplantar / diagnosis*
  • Male
  • Syndrome