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Annu Rev Biochem. 2007;76:751-80.

The machines that divide and fuse mitochondria.

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Section of Molecular and Cellular Biology, University of California, Davis, California 95616, USA.


Mitochondria are derived from eubacteria; however, in most eukaryotes, novel mechanisms for the propagation of this organelle and its genome have evolved. This review focuses on what is currently known about the novel molecular machines that divide and fuse mitochondria.

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