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Phys Rev Lett. 2007 Feb 23;98(8):088102. Epub 2007 Feb 20.

DNA migration and separation on surfaces with a microscale dielectrophoretic trap array.

Author information

1
Harvard University, Cambridge, MA 02138, USA.

Abstract

We studied the surface migration of DNA chains driven by a dc electric field across localized dielectrophoretic traps. By adjusting the length scale of the trap array, separation of a selected band of DNA was accomplished with a scaling exponent between mobility and number of base pairs similar to that obtained in capillary electrophoresis. We then provided a model, which predicts the trapping and extension of DNA chains at a dielectrophoretic trap responsible for the surface mobility and separation.

PMID:
17359130
DOI:
10.1103/PhysRevLett.98.088102
[Indexed for MEDLINE]

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