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J Pediatr. 1992 Feb;120(2 Pt 1):261-4.

Association of poor clinical status and heavy exposure to tobacco smoke in patients with cystic fibrosis who are homozygous for the F508 deletion.

Author information

1
Department of Pediatrics, Vanderbilt University Medical School, Nashville, Tennessee 37232-2586.

Abstract

We examined the association between clinical status and exposure to tobacco smoke in 44 patients homozygous for the F508 cystic fibrosis mutation. Heavy exposure to tobacco smoke was significantly associated with lower Shwachman scores, poorer results of pulmonary function tests, and a fivefold increase in the number of pulmonary-related hospitalizations during the previous year.

PMID:
1735823
DOI:
10.1016/s0022-3476(05)80438-x
[Indexed for MEDLINE]

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