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Eur J Clin Nutr. 2008 Feb;62(2):232-7. Epub 2007 Mar 14.

Probiotic capsules do not lower plasma lipids in young women and men.

Author information

1
Department of Food Science and Nutrition, University of Minnesota, St Paul, MN 55108, USA.

Abstract

OBJECTIVE:

To investigate the effect of probiotic capsules on plasma lipids.

DESIGN:

A randomized, single-blinded, placebo-controlled, parallel-arm trial.

SUBJECTS:

Fifty-five normocholesterolemic subjects ages 18-36 (33 premenopausal women and 22 men).

INTERVENTION:

Each subject consumed either three probiotic capsules each containing a total of 10(9) colony-forming units Lactobacillus acidophilus and Bifidobacterium longum and 10-15 mg fructo-oligosaccharide or three placebo capsules daily for 2 months (men) or two menstrual cycles (women). Plasma lipids were measured before and following the intervention (during the early follicular phase for women).

RESULTS:

Plasma concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglyceride were not altered by consumption of probiotic or placebo capsules and were not different between treatment groups following the intervention.

CONCLUSIONS:

These results do not support a beneficial effect of Lactobacillus acidophilus strain DDS-1 and Bifidobacterium longum strain UABL-14 on plasma lipids in normocholesterolemic young women and men.

SPONSORSHIP:

Supported by the Minnesota Agricultural Experiment Station and UAS Laboratories.

PMID:
17356554
DOI:
10.1038/sj.ejcn.1602719
[Indexed for MEDLINE]
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