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Planta Med. 2007 Apr;73(4):366-71. Epub 2007 Mar 12.

Two new depsipeptides from the marine fungus Spicellum roseum.

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1
Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.

Abstract

Investigation of the secondary metabolites of the marine-derived fungus Spicellum roseum yielded two new cyclohexadepsipeptides, spicellamide A (1) and spicellamide B (2). The structures of 1 and 2 were determined based on extensive evaluations of NMR and MS data. The absolute configuration was deduced after hydrolysis using Marfey's method, chiral chromatography, as well as NOESY and modeling data.

PMID:
17354168
DOI:
10.1055/s-2007-967131
[Indexed for MEDLINE]
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