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Phytochemistry. 2007 Apr;68(8):1165-71. Epub 2007 Mar 12.

Antiproliferative and antioxidant activities of a tricin acylated glycoside from sugarcane (Saccharum officinarum) juice.

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Laboratório de Química, Bioquímica e Biologia Molecular de Alimentos, Departamento de Alimentos e Nutrição Experimental, FCF, Universidade de São Paulo, CP 66083, CEP 05314-970, São Paulo, SP, Brazil.


From sugarcane juice, a flavone, identified by spectroscopic methods as tricin-7-O-beta-(6''-methoxycinnamic)-glucoside, was isolated, in addition to orientin. The tricin derivative was shown to have antioxidant activity higher than Trolox by means of the DPPH assay and lower by the beta-carotene/linoleic acid system. It showed in vitro antiproliferative activity against several human cancer cell lines, with higher selectivity toward cells of the breast resistant NIC/ADR line.

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