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Arch Gerontol Geriatr. 2007 Nov-Dec;45(3):273-80. Epub 2007 Mar 6.

Cognitive function and its effects on the quality of life status in the patients with chronic obstructive pulmonary disease (COPD).

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Dokuz Eylul University, School of Physical Therapy and Rehabilitation, Inciralti TR-35340, Izmir, Turkey.


The objective of the present study was to determine the relationships between the cognitive function and quality of life in the patients with chronic obstructive pulmonary disease (COPD). Thirty-two patients with stable COPD (mean age 66.7+/-2.5 years) and 26 healthy community residents (mean age 65.7+/-7.3 years) were included in the present study. Cognitive status was measured using a modified mini mental state examination (MMSE) and quality of life status using the health survey questionnaire short form-36 (SF-36). The patients with COPD were mildly hypoxemic and their lung function was significantly poorer than in the healthy group (p=0.001). The quality of life scores were lower in the patients with COPD than in the healthy subjects (p=0.01). Impaired cognitive function in the patients with COPD and healthy subjects was not found (the mean MMSE scores 24.8+/-2.0 versus 25.4+/-3.2 for COPD and healthy groups, respectively, p=0.49). No correlation was found between the SF-36 and MMSE and spirometric values in either of groups (p>0.05). In conclusion, the cognitive function of COPD patients with mild hypoxemia may not be impaired in spite of their poor quality of life status.

[Indexed for MEDLINE]

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