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J Nat Prod. 2007 Apr;70(4):652-5. Epub 2007 Mar 8.

Triterpene saponins from Bacopa monnieri and their antidepressant effects in two mice models.

Author information

1
Department of Phytochemistry, College of Pharmacy, Second Military Medical University, Shanghai 200433, People's Republic of China.

Abstract

Three new triterpene glycosides, bacopasides VI-VIII (1-3), together with three known analogues, bacopaside I (4), bacopaside II (5), and bacopasaponsin C (6), were isolated from the whole plant of Bacopa monnieri. Compounds 4, 5, and 6 showed antidepressant activity when tested on forced swimming and tail suspension in mice, respectively.

PMID:
17343408
DOI:
10.1021/np060470s
[Indexed for MEDLINE]

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