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Nat Rev Neurosci. 2007 Apr;8(4):262-75.

Molecular mechanisms of memory reconsolidation.

Author information

1
Department of Psychiatry, Division of Molecular Psychiatry, Center for Genes and Behavior, Yale University School of Medicine, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, 34 Park Street, New Haven, Connecticut 06508, USA.

Abstract

Memory reconsolidation has been argued to be a distinct process that serves to maintain, strengthen or modify memories. Specifically, the retrieval of a previously consolidated memory has been hypothesized to induce an additional activity-dependent labile period during which the memory can be modified. Understanding the molecular mechanisms of reconsolidation could provide crucial insights into the dynamic aspects of normal mnemonic function and psychiatric disorders that are characterized by exceptionally strong and salient emotional memories.

PMID:
17342174
DOI:
10.1038/nrn2090
[Indexed for MEDLINE]

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