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Dev Cell. 2007 Mar;12(3):320-2.

Special delivery: dynamic targeting via cortical capture of microtubules.

Author information

1
University of Pennsylvania School of Medicine, D400 Richards Building, 3700 Hamilton Walk, Philadelphia, PA 19104, USA.

Abstract

Gap junction formation depends on the proper transport of connexin hemichannels to sites of cell-cell contact. Recently in Cell, Shaw et al. implicate microtubule tip tracking proteins in the trafficking of connexin43 to adherens junctions (Shaw et al., 2007). This finding suggests a mechanism for targeted delivery of membrane proteins by microtubule capture at the cortex.

PMID:
17336896
DOI:
10.1016/j.devcel.2007.02.012
[Indexed for MEDLINE]
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