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Yonsei Med J. 2007 Feb 28;48(1):142-6.

An ovarian steroid cell tumor causing virilization and massive ascites.

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Department of Obstetrics and Gynecology, Yonsei University College of Medicine, 135 Shinchon-dong Seodaemun-gu, Seoul 120-752, Korea.


Steroid cell tumors, not otherwise specified (NOS), are rare ovarian sex cord-stromal tumors with malignant potential. The majority of these tumors produce several steroids, particularly testosterone. Various virilizing symptoms such as hirsutism, temporal balding, and amenorrhea are common in these patients; however massive ascites is an infrequent symptom. A 52-year-old woman with the sudden onset of virilization and massive ascites presented for treatment at Severance Hospital. After clinical evaluation, the patient underwent an exploratory laparotomy and a complete surgical staging procedure. She recovered from the surgery uneventfully and was discharged from the hospital five days after surgery. We present here an unusual case of an ovarian steroid cell tumor, NOS, and a brief review of the literature regarding these types of tumors.

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