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Clin Pediatr (Phila). 2007 Mar;46(2):121-6.

Absence of tooth staining with doxycycline treatment in young children.

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Department of Pediatrics C, Asthma Clinic, Schneider Children's Medical Center of Israel, 14 Kaplan Street, Petah Tiqwa 49202, Israel.


The aim of the study was to determine if doxycycline causes tooth staining in young children. A dentist examined 31 randomized children who had been treated with doxycycline and 30 children who had not received doxycycline. Mean age of the children was 10.4 -/+ 2.1 years. Mean age at receipt of the first doxycycline treatment was 4.1 -/+ 1.6 years, and mean number of doxycycline courses was 2.0 -/+ 1.3. No tooth staining was detected by the dentist in any of the children in either group. These findings indicate that treatment with doxycycline in children aged 2 to 8 years is not associated with tooth staining.

[Indexed for MEDLINE]

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