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Cell. 2007 Feb 23;128(4):647-50.

Centromere assembly and propagation.

Author information

1
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. cmorris@hms.harvard.edu

Abstract

Centromere assembly provides a unique example of how elaborate protein structures can be assembled onto DNA, independent of sequence, and then stably propagated through numerous cell divisions. Here, we review the possible epigenetic strategies that organisms ranging from yeast to human use to assemble and propagate active centromeres.

PMID:
17320502
DOI:
10.1016/j.cell.2007.02.002
[Indexed for MEDLINE]
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