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J Pediatr. 2007 Mar;150(3):315-7, 317.e2.

Transient neonatal hypothyroidism is associated with elevated serum anti-thyroglobulin antibody levels in newborns and their mothers.

Author information

1
Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. arash_ordookhani@yahoo.com

Abstract

Transient congenital hypothyroidism (TCH) was detected in 6 of 35,067 newborns (1:5845 births) screened in Iran. Antithyroglobulin antibodies positivity was present in 4 of 6 (66.7%) of those with TCH and in 6 of 106 (5.7%) of those with "transient hyperthyrotropinemia and normal" diagnoses (P = .0005), but positivity was similar in newborns with transient hyperthyrotropinemia versus normal neonates (P = .397).

PMID:
17307555
DOI:
10.1016/j.jpeds.2006.11.034
[Indexed for MEDLINE]

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