Format

Send to

Choose Destination
See comment in PubMed Commons below
Lancet Neurol. 2007 Mar;6(3):237-44.

Genetics of cavernous angiomas.

Author information

1
INSERM, U740, Paris, France.

Abstract

Cerebral cavernous malformations (CCM) are vascular malformations that can occur as a sporadic or a familial autosomal dominant disorder. Clinical and cerebral MRI data on large series of patients with a genetic form of the disease are now available. In addition, three CCM genes have been identified: CCM1/KRIT1, CCM2/MGC4607, and CCM3/PDCD10. These recent developments in clinical and molecular genetics have given us useful information about clinical care and genetic counselling and have broadened our understanding of the mechanisms of this disorder.

PMID:
17303530
DOI:
10.1016/S1474-4422(07)70053-4
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center