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Infect Immun. 2007 Jun;75(6):3202-4. Epub 2007 Feb 12.

The phase-variable allele of the pilus glycosylation gene pglA is not strongly associated with strains of Neisseria gonorrhoeae isolated from patients with disseminated gonococcal infection.

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1
School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.

Abstract

The Neisseria gonorrhoeae pglA gene has two alleles, one of which is phase variable. A previous study reported that all disseminated gonococcal infection (DGI) isolates contained the phase-variable allele and proposed a causal link. In the present study of 81 strains no absolute correlation between DGI and the phase-variable pglA allele was observed.

PMID:
17296763
PMCID:
PMC1932893
DOI:
10.1128/IAI.01501-06
[Indexed for MEDLINE]
Free PMC Article
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