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Ann Nucl Med. 2006 Nov;20(9):583-8.

PET kinetic analysis--compartmental model.

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1
Department of Investigative Radiology, National Cardiovascular Center Research Institute, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan. watabe@ri.ncvc.go.jp

Abstract

PET enables not only visualization of the distribution of radiotracer, but also has ability to quantify several biomedical functions. Compartmental model is a basic idea to analyze dynamic PET data. This review describes the principle of the compartmental model and categorizes the techniques and approaches for the compartmental model according to various aspects: model design, experimental design, invasiveness, and mathematical solution. We also discussed advanced applications of the compartmental analysis with PET.

PMID:
17294668
[Indexed for MEDLINE]
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