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Appl Environ Microbiol. 2007 Apr;73(7):2364-8. Epub 2007 Feb 9.

Nickel-resistant determinant from Leptospirillum ferriphilum.

Author information

1
Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing 100081, China.

Abstract

Leptospirillum ferriphilum strain UBK03 isolated from a mine in Jiangxi, China, is resistant to Ni(2+) (30 to 40 mM). A four-gene nickel resistance cluster was identified and, when transformed into Escherichia coli, enabled growth in 6 mM nickel. Mutation experiments revealed that the genes ncrA, ncrB, and ncrC could confer nickel resistance in Escherichia coli, whereas the gene ncrY could have a negative effect on nickel resistance.

PMID:
17293508
PMCID:
PMC1855658
DOI:
10.1128/AEM.00207-07
[Indexed for MEDLINE]
Free PMC Article

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