Format

Send to

Choose Destination
Cancer Cell. 2007 Feb;11(2):99-101.

Inflammatory tales of liver cancer.

Author information

1
Signaling Systems Laboratory, University of California, San Diego, La Jolla, CA 92093, USA.

Abstract

Cell culture studies have established NF-kappaB's critical role in cancer cell survival and proliferation and led to the clinical use of NF-kappaB inhibitors. However, a paper in this issue of Cancer Cell reveals an anticancer function for NF-kappaB in a mouse model where NF-kappaB activity is lost specifically in hepatocytes. These studies suggest careful examination of NF-kappaB inhibitors as a therapeutic modality for cancer.

PMID:
17292819
DOI:
10.1016/j.ccr.2007.01.008
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center