Format

Send to

Choose Destination
Vaccine. 2007 Jul 26;25(30):5563-76. Epub 2006 Dec 22.

West Nile virus: recent trends in diagnosis and vaccine development.

Author information

1
AFSSA Alfort, UMR1161 (INRA-AFSSA-ENVA), 23 av Général de Gaulle, 94703 Maisons-Alfort Cedex, France.

Abstract

West Nile virus (WNV) is a mosquito-borne flavivirus, native to Africa, Europe, and Western Asia. In many respects, WNV is an outstanding example of a zoonotic pathogen that has leaped geographical barriers and can cause severe disease in human and horse. Before the emergence of WNV in the USA, only few methods of diagnosis were available. Recently, many changes in the fields of WN diagnosis and prevention have happened. This paper will review all these new tools. After a description of the main concerns in WNV and West Nile (WN) disease in humans and animals, this review will present the main available tests for serology and virology detection, from gold standard tests to more recently developed methods. Finally, licensed vaccines and candidate vaccines developed in humans, horses and birds will also been described.

PMID:
17292514
DOI:
10.1016/j.vaccine.2006.12.005
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center