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Cell. 2007 Feb 9;128(3):425-30.

Chemical genetics: where genetics and pharmacology meet.

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1
Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA.

Abstract

Genetics and pharmacology can elicit surprisingly different phenotypes despite targeting the same protein. This Essay explores these unexpected differences and their implications for biology and medicine.

PMID:
17289560
DOI:
10.1016/j.cell.2007.01.021
[Indexed for MEDLINE]
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