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Am J Psychiatry. 1992 Jan;149(1):118-20.

Abnormal intracellular calcium ion concentration in platelets and lymphocytes of bipolar patients.

Author information

1
Department of Psychiatry, University of Colorado, School of Medicine, Denver.

Abstract

The authors measured intracellular Ca2+ concentrations in four manic and five bipolar depressed patients and seven comparison subjects. Platelet and lymphocyte intracellular Ca2+ concentrations were comparable. The patients' mean intracellular Ca2+ concentrations were higher than those of the comparison subjects and demonstrated more interindividual variation. These findings suggest a diffuse abnormality in mechanisms affecting intracellular calcium homeostasis in bipolar disorder.

PMID:
1728159
DOI:
10.1176/ajp.149.1.118
[Indexed for MEDLINE]

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