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Antioxid Redox Signal. 2007 Apr;9(4):515-25.

Adulteration of mustard cooking oil with argemone oil: do Indian food regulatory policies and antioxidant therapy both need revisitation?

Author information

1
Food Toxicology Laboratory, Industrial Toxicology Research Centre, Lucknow, India.

Abstract

Consumption of adulterated mustard oil (Brassica nigra) with argemone oil (Argemone mexicana) even for a short duration leads to a clinical condition referred as epidemic dropsy. In humans, argemone oil contained in adulterated mustard oil causes oxidative stress and death of red blood cells via met-hemoglobin formation by altering pyridine nucleotide(s) and glutathione redox potential. Argemone oil contamination poses a serious threat to human health and should be checked by appropriate regulatory measures. Antioxidant therapy provides symptomatic relief and should be seriously considered for therapeutic interventions against argemone oil toxicity.

PMID:
17280492
DOI:
10.1089/ars.2006.1492
[Indexed for MEDLINE]

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