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Antioxid Redox Signal. 2007 Apr;9(4):515-25.

Adulteration of mustard cooking oil with argemone oil: do Indian food regulatory policies and antioxidant therapy both need revisitation?

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Food Toxicology Laboratory, Industrial Toxicology Research Centre, Lucknow, India.


Consumption of adulterated mustard oil (Brassica nigra) with argemone oil (Argemone mexicana) even for a short duration leads to a clinical condition referred as epidemic dropsy. In humans, argemone oil contained in adulterated mustard oil causes oxidative stress and death of red blood cells via met-hemoglobin formation by altering pyridine nucleotide(s) and glutathione redox potential. Argemone oil contamination poses a serious threat to human health and should be checked by appropriate regulatory measures. Antioxidant therapy provides symptomatic relief and should be seriously considered for therapeutic interventions against argemone oil toxicity.

[Indexed for MEDLINE]

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