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Ophthalmic Surg Lasers Imaging. 2007 Jan-Feb;38(1):27-34. doi: 10.3928/15428877-20070101-04.

Imaging of iris lesions with high-speed optical coherence tomography.

Author information

1
From the Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Abstract

BACKGROUND AND OBJECTIVES:

To image and measure iris tumors with optical coherence tomography (OCT).

PATIENTS AND METHODS:

High-speed (2,000-4,000 axial-scan/sec and 4-16 frames/sec) 1.3-micron wavelength anterior segment OCT prototypes were used to image 6 eyes of 6 patients with a variety of iris lesions, including focal iris nevus, diffuse iris nevus, amelanotic iris nevus, iris melanocytosis, and iris melanoma. OCT images were compared with slit-lamp photography and ultrasound biomicroscopy.

RESULTS:

OCT at 1.3-micron wavelength could penetrate the full thickness of the iris lesions and allow three-dimensional measurement of lesion size. Internal reflectivity is correlated with pigmentation. OCT is a convenient non-contact method that provides imaging of the clinically important angle structures (scleral spur and angle recess).

CONCLUSIONS:

OCT is a new imaging modality that complements slit-lamp photography and ultrasound biomicroscopy for serial evaluation of iris

PMID:
17278533
DOI:
10.3928/15428877-20070101-04
[Indexed for MEDLINE]

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