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Arch Microbiol. 2007 Jun;187(6):433-9. Epub 2007 Feb 3.

Regulation of the chitobiose-phosphotransferase system in Vibrio cholerae.

Author information

1
Institut für Hygiene und Mikrobiologie, Universität Würzburg, Josef Schneider Str. 2, E1, 97080 Würzburg, Germany.

Abstract

Vibrio cholerae harbours a phosphotransferase system (PTS) enabling the organism to utilise chitosan oligosaccharide, e.g. derived from deacetylated chitin. As shown recently, this utilization system is encoded by the ORFs VC1281-1283 (Meibom et al. in Proc Natl Acad Sci USA, 101:2524-2529, 2004). By using a transcriptional reporter fusion technique, we identified the regulator of the system and characterised gene expression. Furthermore, we found that gene expression of this PTS system is influenced by catabolite regulation and also by an Mlc homologue (VC2007), which in E. coli is a global regulator of sugar metabolism.

PMID:
17277949
DOI:
10.1007/s00203-006-0207-4
[Indexed for MEDLINE]

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