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Br J Psychiatry. 2007 Feb;190:174-5.

Localisation of increased prefrontal white matter in pathological liars.

Author information

  • 1Department of Psychology, University of Southern California, Los Angeles, and David Geffen School of Medicine, CA 90089-1061, USA. yalingy@usc.edu

Abstract

We examined white matter volumes in four prefrontal subregions using structural magnetic resonance imaging in 10 pathological liars, 14 antisocial controls, and 20 normal controls. Liars showed a relatively widespread increase in white matter (23-36%) in orbitofrontal, middle and inferior, but not superior, frontal gyri compared with antisocial and normal controls. This white matter increase may predispose some individuals to pathological lying.

PMID:
17267937
PMCID:
PMC2376803
DOI:
10.1192/bjp.bp.106.025056
[PubMed - indexed for MEDLINE]
Free PMC Article
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