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Radiother Oncol. 2007 Feb;82(2):185-90. Epub 2007 Jan 24.

Image-guided robotic radiosurgery for spinal metastases.

Author information

1
Department of Radiation Oncology, Stanford University, Stanford, CA 94305-5847, USA. iris.gibbs@stanford.edu

Abstract

BACKGROUND AND PURPOSE:

To determine the effectiveness and safety of image-guided robotic radiosurgery for spinal metastases.

MATERIALS/METHODS:

From 1996 to 2005, 74 patients with 102 spinal metastases were treated using the CyberKnife at Stanford University. Sixty-two (84%) patients were symptomatic. Seventy-four percent (50/68) of previously treated patients had prior radiation. Using the CyberKnife, 16-25 Gy in 1-5 fractions was delivered. Patients were followed clinically and radiographically for at least 3 months or until death.

RESULTS:

With mean follow-up of 9 months (range 0-33 months), 36 patients were alive and 38 were dead at last follow-up. No death was treatment related. Eighty-four (84%) percent of symptomatic patients experienced improvement or resolution of symptoms after treatment. Three patients developed treatment-related spinal injury. Analysis of dose-volume parameters and clinical parameters failed to identify predictors of spinal cord injury.

CONCLUSIONS:

Robotic radiosurgery is effective and generally safe for spinal metastases even in previously irradiated patients.

PMID:
17257702
DOI:
10.1016/j.radonc.2006.11.023
[Indexed for MEDLINE]

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