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J Antibiot (Tokyo). 2006 Nov;59(11):720-3.

A new hydrogenated azaphilone Sch 725680 from Aspergillus sp.

Author information

1
Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. shu-wei.yang@spcorp.com

Abstract

A new hydrogenated azaphilone Sch725680 (1) was isolated and identified from the culture of an Aspergillus sp. The structure elucidation of 1 was achieved based on extensive NMR spectroscopic analyses. Compound 1 showed inhibitory activity against Saccharomyces cerevisiae (PM503) and Candida albicans (C43) with MICs of 8 and 64 microg/ml, respectively.

PMID:
17256471
DOI:
10.1038/ja.2006.96
[Indexed for MEDLINE]
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