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Immunol Today. 1991 Dec;12(12):447-55.

Naturally-occurring peptide antigens derived from the MHC class-I-restricted processing pathway.

Author information

1
Max-Planck-Institut für Biologie, Abteilung Immungenetik, Tübingen, FRG.

Abstract

The extraction of naturally-processed peptides from MHC class I glycoproteins has paved the way for a major advance in the understanding of the antigen processing pathway that ultimately induces cytotoxic T-cell responses. Here, Olaf Rötzschke and Kirsten Falk review these new developments and discuss their findings in terms of a novel hypothesis of MHC class-I-restricted processing.

PMID:
1723878
DOI:
10.1016/0167-5699(91)90018-O
[Indexed for MEDLINE]
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