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Nat Rev Neurosci. 2007 Feb;8(2):141-51.

Neuronal migration in the adult brain: are we there yet?

Author information

1
UNC Neuroscience Center and the Department of Cell and Molecular Physiology, Room 7109B, 103 Mason Farm Road, The University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7250, USA.

Abstract

The generation and targeting of appropriate numbers and types of neurons to where they are needed in the brain is essential for the establishment, maintenance and modification of neural circuitry. This review aims to summarize the patterns, mechanisms and functional significance of neuronal migration in the postnatal brain, with an emphasis on the migratory events that persist in the mature brain.

PMID:
17237805
DOI:
10.1038/nrn2074
[Indexed for MEDLINE]

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