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Pflugers Arch. 2007 Aug;454(5):805-19. Epub 2007 Jan 17.

Phototransduction in mouse rods and cones.

Author information

1
Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. fuyingbi@mail.jhmi.edu

Abstract

Phototransduction is the process by which light triggers an electrical signal in a photoreceptor cell. Image-forming vision in vertebrates is mediated by two types of photoreceptors: the rods and the cones. In this review, we provide a summary of the success in which the mouse has served as a vertebrate model for studying rod phototransduction, with respect to both the activation and termination steps. Cones are still not as well-understood as rods partly because it is difficult to work with mouse cones due to their scarcity and fragility. The situation may change, however.

PMID:
17226052
PMCID:
PMC2877390
DOI:
10.1007/s00424-006-0194-y
[Indexed for MEDLINE]
Free PMC Article

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