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J Cyst Fibros. 2007 Jul;6(4):304-8. Epub 2007 Jan 12.

Early inflammation in the airways of a cystic fibrosis foetus.

Author information

1
Department of Human Genetics, Center for Biomedical Integrative Genoproteomics (CBIG), University of Liege, CHU Sart-Tilman B35, B-4000 Liege, Belgium.

Abstract

In cystic fibrosis patients, inflammation is often considered to be secondary to chronic infections. In the present study, we show increased levels of pro-inflammatory proteins in the lungs of a cystic fibrosis foetus compared to the lungs of two normal foetuses. Our findings suggest therefore the existence of an early intrinsic pro-inflammatory state in cystic fibrosis airways.

PMID:
17223612
DOI:
10.1016/j.jcf.2006.12.001
[Indexed for MEDLINE]
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