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Scand J Dent Res. 1991 Dec;99(6):519-21.

Neuropeptides in temporomandibular joints with rheumatoid arthritis: a clinical study.

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1
Department of Clinical Oral Physiology, Karolinska Institutet, Huddinge, Sweden.

Abstract

There is evidence that neuropeptides play a role in the development of arthritis. Synovial fluid from arthritic temporomandibular joints in patients with rheumatoid arthritis was therefore investigated for presence of the neuropeptides calcitonin gene-related peptide, substance P, neurokinin A and neuropeptide Y. All four peptides were found in the synovial fluid above plasma level, but calcitonin gene-related peptide showed the highest concentration and substance P the lowest.

PMID:
1722347
[Indexed for MEDLINE]
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