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Infect Immun. 2007 Mar;75(3):1524-33. Epub 2007 Jan 12.

SiiE is secreted by the Salmonella enterica serovar Typhimurium pathogenicity island 4-encoded secretion system and contributes to intestinal colonization in cattle.

Author information

1
Division of Microbiology, Institute for Animal Health, Compton, Nr Newbury, Berkshire, RG20 7NN, United Kingdom. eirwen.morgan@bbsrc.ac.uk

Abstract

Here we report that Salmonella enterica serovar Typhimurium pathogenicity island 4 carries a type I secretion system (siiCDF) which secretes an approximately 600-kDa protein (encoded by siiE). SiiE is surface expressed, and its production is regulated by HilA. SiiE and SiiF influence colonization in cattle and the invasion of bovine enterocytes.

PMID:
17220313
PMCID:
PMC1828598
DOI:
10.1128/IAI.01438-06
[Indexed for MEDLINE]
Free PMC Article
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