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Schizophr Bull. 2007 May;33(3):757-60. Epub 2007 Jan 11.

Effects of toxoplasma on human behavior.

Author information

1
Departmeent of Parasitology, Faculty of Science, Charles University, Vinicná 7, CZ-128 44 Praha 2, Czech Republic. flegr@cesnet.cz

Abstract

Although latent infection with Toxoplasma gondii is among the most prevalent of human infections, it has been generally assumed that, except for congenital transmission, it is asymptomatic. The demonstration that latent Toxoplasma infections can alter behavior in rodents has led to a reconsideration of this assumption. When infected human adults were compared with uninfected adults on personality questionnaires or on a panel of behavioral tests, several differences were found. Other studies have demonstrated reduced psychomotor performance in affected individuals. Possible mechanisms by which T. gondii may affect human behavior include its effect on dopamine and on testosterone.

PMID:
17218612
PMCID:
PMC2526142
DOI:
10.1093/schbul/sbl074
[Indexed for MEDLINE]
Free PMC Article

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