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Org Lett. 2007 Jan 18;9(2):303-5.

Multicomponent synthesis of 3-indolepropionic acids.

Author information

1
Centre for Synthesis and Chemical Biology, Department of Pharmaceutical and Medicinal Chemistry, The Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Dublin, Ireland. madamo@rcsi.ie

Abstract

A three-component one-pot procedure (3-MC) was developed to assemble 3-indolepropionic acids from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography. [reaction: see text].

PMID:
17217290
DOI:
10.1021/ol0627698
[Indexed for MEDLINE]
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